Ancora: a web resource for exploring highly conserved noncoding elements and their association with developmental regulatory genes

Metazoan genomes contain arrays of highly conserved noncoding elements (HCNEs) that span developmental regulatory genes and define regulatory domains. We describe Ancora , a web resource that provides data and tools for exploring genomic organization of HCNEs for multiple genomes. Ancora includes a...

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Detalles Bibliográficos
Autores principales: Engström, Pär G, Fredman, David, Lenhard, Boris
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374709/
https://www.ncbi.nlm.nih.gov/pubmed/18279518
http://dx.doi.org/10.1186/gb-2008-9-2-r34
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author Engström, Pär G
Fredman, David
Lenhard, Boris
author_facet Engström, Pär G
Fredman, David
Lenhard, Boris
author_sort Engström, Pär G
collection PubMed
description Metazoan genomes contain arrays of highly conserved noncoding elements (HCNEs) that span developmental regulatory genes and define regulatory domains. We describe Ancora , a web resource that provides data and tools for exploring genomic organization of HCNEs for multiple genomes. Ancora includes a genome browser that shows HCNE locations and features novel HCNE density plots as a powerful tool to discover developmental regulatory genes and distinguish their regulatory elements and domains.
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spelling pubmed-23747092008-05-09 Ancora: a web resource for exploring highly conserved noncoding elements and their association with developmental regulatory genes Engström, Pär G Fredman, David Lenhard, Boris Genome Biol Software Metazoan genomes contain arrays of highly conserved noncoding elements (HCNEs) that span developmental regulatory genes and define regulatory domains. We describe Ancora , a web resource that provides data and tools for exploring genomic organization of HCNEs for multiple genomes. Ancora includes a genome browser that shows HCNE locations and features novel HCNE density plots as a powerful tool to discover developmental regulatory genes and distinguish their regulatory elements and domains. BioMed Central 2008 2008-02-15 /pmc/articles/PMC2374709/ /pubmed/18279518 http://dx.doi.org/10.1186/gb-2008-9-2-r34 Text en Copyright © 2008 Engström et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an open access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Software
Engström, Pär G
Fredman, David
Lenhard, Boris
Ancora: a web resource for exploring highly conserved noncoding elements and their association with developmental regulatory genes
title Ancora: a web resource for exploring highly conserved noncoding elements and their association with developmental regulatory genes
title_full Ancora: a web resource for exploring highly conserved noncoding elements and their association with developmental regulatory genes
title_fullStr Ancora: a web resource for exploring highly conserved noncoding elements and their association with developmental regulatory genes
title_full_unstemmed Ancora: a web resource for exploring highly conserved noncoding elements and their association with developmental regulatory genes
title_short Ancora: a web resource for exploring highly conserved noncoding elements and their association with developmental regulatory genes
title_sort ancora: a web resource for exploring highly conserved noncoding elements and their association with developmental regulatory genes
topic Software
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374709/
https://www.ncbi.nlm.nih.gov/pubmed/18279518
http://dx.doi.org/10.1186/gb-2008-9-2-r34
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