Intron mis-splicing: no alternative?

A recent report reveals widespread mis-splicing of RNA transcripts in eukaryotes, with mis-spliced RNA destroyed by nonsense-mediated mRNA decay. This striking inefficiency deepens the mystery of the proliferation and persistence of introns.

Detalles Bibliográficos
Autores principales: Roy, Scott William, Irimia, Manuel
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374719/
https://www.ncbi.nlm.nih.gov/pubmed/18304372
http://dx.doi.org/10.1186/gb-2008-9-2-208
Descripción
Sumario:A recent report reveals widespread mis-splicing of RNA transcripts in eukaryotes, with mis-spliced RNA destroyed by nonsense-mediated mRNA decay. This striking inefficiency deepens the mystery of the proliferation and persistence of introns.

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