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Intron mis-splicing: no alternative?
A recent report reveals widespread mis-splicing of RNA transcripts in eukaryotes, with mis-spliced RNA destroyed by nonsense-mediated mRNA decay. This striking inefficiency deepens the mystery of the proliferation and persistence of introns.
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374719/ https://www.ncbi.nlm.nih.gov/pubmed/18304372 http://dx.doi.org/10.1186/gb-2008-9-2-208 |
| _version_ | 1782154519984996352 |
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| author | Roy, Scott William Irimia, Manuel |
| author_facet | Roy, Scott William Irimia, Manuel |
| author_sort | Roy, Scott William |
| collection | PubMed |
| description | A recent report reveals widespread mis-splicing of RNA transcripts in eukaryotes, with mis-spliced RNA destroyed by nonsense-mediated mRNA decay. This striking inefficiency deepens the mystery of the proliferation and persistence of introns. |
| format | Text |
| id | pubmed-2374719 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2008 |
| publisher | BioMed Central |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-23747192008-05-09 Intron mis-splicing: no alternative? Roy, Scott William Irimia, Manuel Genome Biol Minireview A recent report reveals widespread mis-splicing of RNA transcripts in eukaryotes, with mis-spliced RNA destroyed by nonsense-mediated mRNA decay. This striking inefficiency deepens the mystery of the proliferation and persistence of introns. BioMed Central 2008 2008-02-19 /pmc/articles/PMC2374719/ /pubmed/18304372 http://dx.doi.org/10.1186/gb-2008-9-2-208 Text en Copyright © 2008 BioMed Central Ltd |
| spellingShingle | Minireview Roy, Scott William Irimia, Manuel Intron mis-splicing: no alternative? |
| title | Intron mis-splicing: no alternative? |
| title_full | Intron mis-splicing: no alternative? |
| title_fullStr | Intron mis-splicing: no alternative? |
| title_full_unstemmed | Intron mis-splicing: no alternative? |
| title_short | Intron mis-splicing: no alternative? |
| title_sort | intron mis-splicing: no alternative? |
| topic | Minireview |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374719/ https://www.ncbi.nlm.nih.gov/pubmed/18304372 http://dx.doi.org/10.1186/gb-2008-9-2-208 |
| work_keys_str_mv | AT royscottwilliam intronmissplicingnoalternative AT irimiamanuel intronmissplicingnoalternative |