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Genome wide prediction of HNF4α functional binding sites by the use of local and global sequence context
We report an application of machine learning algorithms that enables prediction of the functional context of transcription factor binding sites in the human genome. We demonstrate that our method allowed de novo identification of hepatic nuclear factor (HNF)4α binding sites and significantly improve...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374721/ https://www.ncbi.nlm.nih.gov/pubmed/18291023 http://dx.doi.org/10.1186/gb-2008-9-2-r36 |