Whole genome functional analysis identifies novel components required for mitotic spindle integrity in human cells

BACKGROUND: The mitotic spindle is a complex mechanical apparatus required for accurate segregation of sister chromosomes during mitosis. We designed a genetic screen using automated microscopy to discover factors essential for mitotic progression. Using a RNA interference library of 49,164 double-s...

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Detalles Bibliográficos
Autores principales: Rines, Daniel R, Gomez-Ferreria, Maria Ana, Zhou, Yingyao, DeJesus, Paul, Grob, Seanna, Batalov, Serge, Labow, Marc, Huesken, Dieter, Mickanin, Craig, Hall, Jonathan, Reinhardt, Mischa, Natt, Francois, Lange, Joerg, Sharp, David J, Chanda, Sumit K, Caldwell, Jeremy S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374723/
https://www.ncbi.nlm.nih.gov/pubmed/18302737
http://dx.doi.org/10.1186/gb-2008-9-2-r44

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