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The Goldbeter-Koshland Switch in the First-Order Region and Its Response to Dynamic Disorder
In their classical work (Proc. Natl. Acad. Sci. USA, 1981, 78:6840–6844), Goldbeter and Koshland mathematically analyzed a reversible covalent modification system which is highly sensitive to the concentration of effectors. Its signal-response curve appears sigmoidal, constituting a biochemical swit...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374878/ https://www.ncbi.nlm.nih.gov/pubmed/18478088 http://dx.doi.org/10.1371/journal.pone.0002140 |