Cargando…
Replicative Senescence of Mesenchymal Stem Cells: A Continuous and Organized Process
Mesenchymal stem cells (MSC) comprise a promising tool for cellular therapy. These cells are usually culture expanded prior to their application. However, a precise molecular definition of MSC and the sequel of long-term in vitro culture are yet unknown. In this study, we have addressed the impact o...
Autores principales: | Wagner, Wolfgang, Horn, Patrick, Castoldi, Mirco, Diehlmann, Anke, Bork, Simone, Saffrich, Rainer, Benes, Vladimir, Blake, Jonathon, Pfister, Stefan, Eckstein, Volker, Ho, Anthony D. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374903/ https://www.ncbi.nlm.nih.gov/pubmed/18493317 http://dx.doi.org/10.1371/journal.pone.0002213 |
Ejemplares similares
-
Aging and Replicative Senescence Have Related Effects on Human Stem and Progenitor Cells
por: Wagner, Wolfgang, et al.
Publicado: (2009) -
Co-culture with mesenchymal stromal cells increases proliferation and maintenance of haematopoietic progenitor cells
por: Walenda, Thomas, et al.
Publicado: (2010) -
Senescence‐associated DNA methylation is stochastically acquired in subpopulations of mesenchymal stem cells
por: Franzen, Julia, et al.
Publicado: (2016) -
The Many Facets of SDF-1α, CXCR4 Agonists and Antagonists on Hematopoietic Progenitor Cells
por: Faber, Anne, et al.
Publicado: (2007) -
DNA methylation pattern changes upon long-term culture and aging of human mesenchymal stromal cells
por: Bork, Simone, et al.
Publicado: (2010)