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Silencing of GM3 synthase suppresses lung metastasis of murine breast cancer cells

BACKGROUND: Gangliosides are sialic acid containing glycosphingolipids that are ubiquitously distributed on vertebrate plasma membranes. GM3, a precursor for most of the more complex ganglioside species, is synthesized by GM3 synthase. Although total ganglioside levels are significantly higher in br...

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Detalles Bibliográficos
Autores principales:	Gu, Yuchao, Zhang, Junhua, Mi, Wenyi, Yang, Jing, Han, Feng, Lu, Xinzhi, Yu, Wengong
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374951/ https://www.ncbi.nlm.nih.gov/pubmed/18171481 http://dx.doi.org/10.1186/bcr1841

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