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Na(+)/H(+ )exchanger regulatory factor 1 inhibits platelet-derived growth factor signaling in breast cancer cells

INTRODUCTION: The gene encoding Na(+)/H(+ )exchanger regulatory factor 1 (NHERF1) is a putative tumor suppressor gene that harbors frequent loss of heterozygosity (LOH) and intragenic mutations in breast carcinoma. The exact biologic activity of NHERF1 in mammary glands, however, remains unclear. It...

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Detalles Bibliográficos
Autores principales: Pan, Yong, Weinman, Edward J, Le Dai, Jia
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374956/
https://www.ncbi.nlm.nih.gov/pubmed/18190691
http://dx.doi.org/10.1186/bcr1846

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