Fatal attraction: why breast cancer cells home to bone

Osteolytic metastases due to breast cancer are serious events. The interactions between breast cancer cells with the microenvironment of bone have been thought to provide an ideal milieu for cancer cells. Recent data now indicate that migration of breast cancer cells into bone and their subsequent g...

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Detalles Bibliográficos
Autores principales: Hofbauer, Lorenz C, Rachner, Tilman, Singh, Shiv K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374958/
https://www.ncbi.nlm.nih.gov/pubmed/18226190
http://dx.doi.org/10.1186/bcr1848
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author Hofbauer, Lorenz C
Rachner, Tilman
Singh, Shiv K
author_facet Hofbauer, Lorenz C
Rachner, Tilman
Singh, Shiv K
author_sort Hofbauer, Lorenz C
collection PubMed
description Osteolytic metastases due to breast cancer are serious events. The interactions between breast cancer cells with the microenvironment of bone have been thought to provide an ideal milieu for cancer cells. Recent data now indicate that migration of breast cancer cells into bone and their subsequent growth into metastases depends upon the interaction of the receptor activator of NF-κB ligand (RANKL) with its receptor RANK.
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spelling pubmed-23749582008-05-10 Fatal attraction: why breast cancer cells home to bone Hofbauer, Lorenz C Rachner, Tilman Singh, Shiv K Breast Cancer Res Commentary Osteolytic metastases due to breast cancer are serious events. The interactions between breast cancer cells with the microenvironment of bone have been thought to provide an ideal milieu for cancer cells. Recent data now indicate that migration of breast cancer cells into bone and their subsequent growth into metastases depends upon the interaction of the receptor activator of NF-κB ligand (RANKL) with its receptor RANK. BioMed Central 2008 2008-01-25 /pmc/articles/PMC2374958/ /pubmed/18226190 http://dx.doi.org/10.1186/bcr1848 Text en Copyright © 2008 BioMed Central Ltd
spellingShingle Commentary
Hofbauer, Lorenz C
Rachner, Tilman
Singh, Shiv K
Fatal attraction: why breast cancer cells home to bone
title Fatal attraction: why breast cancer cells home to bone
title_full Fatal attraction: why breast cancer cells home to bone
title_fullStr Fatal attraction: why breast cancer cells home to bone
title_full_unstemmed Fatal attraction: why breast cancer cells home to bone
title_short Fatal attraction: why breast cancer cells home to bone
title_sort fatal attraction: why breast cancer cells home to bone
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374958/
https://www.ncbi.nlm.nih.gov/pubmed/18226190
http://dx.doi.org/10.1186/bcr1848
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AT singhshivk fatalattractionwhybreastcancercellshometobone

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