Re-evaluating early breast neoplasia

Historically, histomorphological and epidemiological data suggested that atypical ductal hyperplasia and ductal carcinoma in situ are the earliest recognizable neoplastic stages of breast cancer progression. Over the past several years, detailed high-throughput molecular genetic, gene expression and...

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Detalles Bibliográficos
Autores principales: Moulis, Sharon, Sgroi, Dennis C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Viewpoint
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374963/
https://www.ncbi.nlm.nih.gov/pubmed/18279539
http://dx.doi.org/10.1186/bcr1853
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author Moulis, Sharon
Sgroi, Dennis C
author_facet Moulis, Sharon
Sgroi, Dennis C
author_sort Moulis, Sharon
collection PubMed
description Historically, histomorphological and epidemiological data suggested that atypical ductal hyperplasia and ductal carcinoma in situ are the earliest recognizable neoplastic stages of breast cancer progression. Over the past several years, detailed high-throughput molecular genetic, gene expression and epigenetic analyses have enhanced our understanding of these early neoplastic lesions and have re-shaped our view of human breast cancer progression to include multiple distinct pathways of evolution.
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spelling pubmed-23749632008-05-10 Re-evaluating early breast neoplasia Moulis, Sharon Sgroi, Dennis C Breast Cancer Res Viewpoint Historically, histomorphological and epidemiological data suggested that atypical ductal hyperplasia and ductal carcinoma in situ are the earliest recognizable neoplastic stages of breast cancer progression. Over the past several years, detailed high-throughput molecular genetic, gene expression and epigenetic analyses have enhanced our understanding of these early neoplastic lesions and have re-shaped our view of human breast cancer progression to include multiple distinct pathways of evolution. BioMed Central 2008 2008-02-08 /pmc/articles/PMC2374963/ /pubmed/18279539 http://dx.doi.org/10.1186/bcr1853 Text en Copyright © 2008 BioMed Central Ltd
spellingShingle Viewpoint
Moulis, Sharon
Sgroi, Dennis C
Re-evaluating early breast neoplasia
title Re-evaluating early breast neoplasia
title_full Re-evaluating early breast neoplasia
title_fullStr Re-evaluating early breast neoplasia
title_full_unstemmed Re-evaluating early breast neoplasia
title_short Re-evaluating early breast neoplasia
title_sort re-evaluating early breast neoplasia
topic Viewpoint
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374963/
https://www.ncbi.nlm.nih.gov/pubmed/18279539
http://dx.doi.org/10.1186/bcr1853
work_keys_str_mv AT moulissharon reevaluatingearlybreastneoplasia
AT sgroidennisc reevaluatingearlybreastneoplasia

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