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Brca1 breast tumors contain distinct CD44(+)/CD24(- )and CD133(+ )cells with cancer stem cell characteristics

INTRODUCTION: Whether cancer stem cells occur in BRCA1-associated breast cancer and contribute to therapeutic response is not known. METHODS: We generated and characterized 16 cell lines from five distinct Brca1deficient mouse mammary tumors with respect to their cancer stem cell characteristics. RE...

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Detalles Bibliográficos
Autores principales:	Wright, Mollie H, Calcagno, Anna Maria, Salcido, Crystal D, Carlson, Marisa D, Ambudkar, Suresh V, Varticovski, Lyuba
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374965/ https://www.ncbi.nlm.nih.gov/pubmed/18241344 http://dx.doi.org/10.1186/bcr1855

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