Model-based analysis of two-color arrays (MA2C)

A novel normalization method based on the GC content of probes is developed for two-color tiling arrays. The proposed method, together with robust estimates of the model parameters, is shown to perform superbly on published data sets. A robust algorithm for detecting peak regions is also formulated...

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Detalles Bibliográficos
Autores principales: Song, Jun S, Johnson, W Evan, Zhu, Xiaopeng, Zhang, Xinmin, Li, Wei, Manrai, Arjun K, Liu, Jun S, Chen, Runsheng, Liu, X Shirley
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375008/
https://www.ncbi.nlm.nih.gov/pubmed/17727723
http://dx.doi.org/10.1186/gb-2007-8-8-r178

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