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The DAVID Gene Functional Classification Tool: a novel biological module-centric algorithm to functionally analyze large gene lists

The DAVID Gene Functional Classification Tool uses a novel agglomeration algorithm to condense a list of genes or associated biological terms into organized classes of related genes or biology, called biological modules. This organization is accomplished by mining the complex biological co-occurrenc...

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Detalles Bibliográficos
Autores principales: Huang, Da Wei, Sherman, Brad T, Tan, Qina, Collins, Jack R, Alvord, W Gregory, Roayaei, Jean, Stephens, Robert, Baseler, Michael W, Lane, H Clifford, Lempicki, Richard A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375021/
https://www.ncbi.nlm.nih.gov/pubmed/17784955
http://dx.doi.org/10.1186/gb-2007-8-9-r183
Descripción
Sumario:The DAVID Gene Functional Classification Tool uses a novel agglomeration algorithm to condense a list of genes or associated biological terms into organized classes of related genes or biology, called biological modules. This organization is accomplished by mining the complex biological co-occurrences found in multiple sources of functional annotation. It is a powerful method to group functionally related genes and terms into a manageable number of biological modules for efficient interpretation of gene lists in a network context.