Cargando…

The DAVID Gene Functional Classification Tool: a novel biological module-centric algorithm to functionally analyze large gene lists

The DAVID Gene Functional Classification Tool uses a novel agglomeration algorithm to condense a list of genes or associated biological terms into organized classes of related genes or biology, called biological modules. This organization is accomplished by mining the complex biological co-occurrenc...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Da Wei, Sherman, Brad T, Tan, Qina, Collins, Jack R, Alvord, W Gregory, Roayaei, Jean, Stephens, Robert, Baseler, Michael W, Lane, H Clifford, Lempicki, Richard A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375021/
https://www.ncbi.nlm.nih.gov/pubmed/17784955
http://dx.doi.org/10.1186/gb-2007-8-9-r183
_version_ 1782154560789282816
author Huang, Da Wei
Sherman, Brad T
Tan, Qina
Collins, Jack R
Alvord, W Gregory
Roayaei, Jean
Stephens, Robert
Baseler, Michael W
Lane, H Clifford
Lempicki, Richard A
author_facet Huang, Da Wei
Sherman, Brad T
Tan, Qina
Collins, Jack R
Alvord, W Gregory
Roayaei, Jean
Stephens, Robert
Baseler, Michael W
Lane, H Clifford
Lempicki, Richard A
author_sort Huang, Da Wei
collection PubMed
description The DAVID Gene Functional Classification Tool uses a novel agglomeration algorithm to condense a list of genes or associated biological terms into organized classes of related genes or biology, called biological modules. This organization is accomplished by mining the complex biological co-occurrences found in multiple sources of functional annotation. It is a powerful method to group functionally related genes and terms into a manageable number of biological modules for efficient interpretation of gene lists in a network context.
format Text
id pubmed-2375021
institution National Center for Biotechnology Information
language English
publishDate 2007
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-23750212008-05-12 The DAVID Gene Functional Classification Tool: a novel biological module-centric algorithm to functionally analyze large gene lists Huang, Da Wei Sherman, Brad T Tan, Qina Collins, Jack R Alvord, W Gregory Roayaei, Jean Stephens, Robert Baseler, Michael W Lane, H Clifford Lempicki, Richard A Genome Biol Software The DAVID Gene Functional Classification Tool uses a novel agglomeration algorithm to condense a list of genes or associated biological terms into organized classes of related genes or biology, called biological modules. This organization is accomplished by mining the complex biological co-occurrences found in multiple sources of functional annotation. It is a powerful method to group functionally related genes and terms into a manageable number of biological modules for efficient interpretation of gene lists in a network context. BioMed Central 2007 2007-09-04 /pmc/articles/PMC2375021/ /pubmed/17784955 http://dx.doi.org/10.1186/gb-2007-8-9-r183 Text en Copyright © 2007 Huang et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an open access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Software
Huang, Da Wei
Sherman, Brad T
Tan, Qina
Collins, Jack R
Alvord, W Gregory
Roayaei, Jean
Stephens, Robert
Baseler, Michael W
Lane, H Clifford
Lempicki, Richard A
The DAVID Gene Functional Classification Tool: a novel biological module-centric algorithm to functionally analyze large gene lists
title The DAVID Gene Functional Classification Tool: a novel biological module-centric algorithm to functionally analyze large gene lists
title_full The DAVID Gene Functional Classification Tool: a novel biological module-centric algorithm to functionally analyze large gene lists
title_fullStr The DAVID Gene Functional Classification Tool: a novel biological module-centric algorithm to functionally analyze large gene lists
title_full_unstemmed The DAVID Gene Functional Classification Tool: a novel biological module-centric algorithm to functionally analyze large gene lists
title_short The DAVID Gene Functional Classification Tool: a novel biological module-centric algorithm to functionally analyze large gene lists
title_sort david gene functional classification tool: a novel biological module-centric algorithm to functionally analyze large gene lists
topic Software
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375021/
https://www.ncbi.nlm.nih.gov/pubmed/17784955
http://dx.doi.org/10.1186/gb-2007-8-9-r183
work_keys_str_mv AT huangdawei thedavidgenefunctionalclassificationtoolanovelbiologicalmodulecentricalgorithmtofunctionallyanalyzelargegenelists
AT shermanbradt thedavidgenefunctionalclassificationtoolanovelbiologicalmodulecentricalgorithmtofunctionallyanalyzelargegenelists
AT tanqina thedavidgenefunctionalclassificationtoolanovelbiologicalmodulecentricalgorithmtofunctionallyanalyzelargegenelists
AT collinsjackr thedavidgenefunctionalclassificationtoolanovelbiologicalmodulecentricalgorithmtofunctionallyanalyzelargegenelists
AT alvordwgregory thedavidgenefunctionalclassificationtoolanovelbiologicalmodulecentricalgorithmtofunctionallyanalyzelargegenelists
AT roayaeijean thedavidgenefunctionalclassificationtoolanovelbiologicalmodulecentricalgorithmtofunctionallyanalyzelargegenelists
AT stephensrobert thedavidgenefunctionalclassificationtoolanovelbiologicalmodulecentricalgorithmtofunctionallyanalyzelargegenelists
AT baselermichaelw thedavidgenefunctionalclassificationtoolanovelbiologicalmodulecentricalgorithmtofunctionallyanalyzelargegenelists
AT lanehclifford thedavidgenefunctionalclassificationtoolanovelbiologicalmodulecentricalgorithmtofunctionallyanalyzelargegenelists
AT lempickiricharda thedavidgenefunctionalclassificationtoolanovelbiologicalmodulecentricalgorithmtofunctionallyanalyzelargegenelists
AT huangdawei davidgenefunctionalclassificationtoolanovelbiologicalmodulecentricalgorithmtofunctionallyanalyzelargegenelists
AT shermanbradt davidgenefunctionalclassificationtoolanovelbiologicalmodulecentricalgorithmtofunctionallyanalyzelargegenelists
AT tanqina davidgenefunctionalclassificationtoolanovelbiologicalmodulecentricalgorithmtofunctionallyanalyzelargegenelists
AT collinsjackr davidgenefunctionalclassificationtoolanovelbiologicalmodulecentricalgorithmtofunctionallyanalyzelargegenelists
AT alvordwgregory davidgenefunctionalclassificationtoolanovelbiologicalmodulecentricalgorithmtofunctionallyanalyzelargegenelists
AT roayaeijean davidgenefunctionalclassificationtoolanovelbiologicalmodulecentricalgorithmtofunctionallyanalyzelargegenelists
AT stephensrobert davidgenefunctionalclassificationtoolanovelbiologicalmodulecentricalgorithmtofunctionallyanalyzelargegenelists
AT baselermichaelw davidgenefunctionalclassificationtoolanovelbiologicalmodulecentricalgorithmtofunctionallyanalyzelargegenelists
AT lanehclifford davidgenefunctionalclassificationtoolanovelbiologicalmodulecentricalgorithmtofunctionallyanalyzelargegenelists
AT lempickiricharda davidgenefunctionalclassificationtoolanovelbiologicalmodulecentricalgorithmtofunctionallyanalyzelargegenelists