DetectiV: visualization, normalization and significance testing for pathogen-detection microarray data

DNA microarrays offer the possibility of testing for the presence of thousands of micro-organisms in a single experiment. However, there is a lack of reliable bioinformatics tools for the analysis of such data. We have developed DetectiV, a package for the statistical software R. DetectiV offers pow...

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Detalles Bibliográficos
Autores principales: Watson, Michael, Dukes, Juliet, Abu-Median, Abu-Bakr, King, Donald P, Britton, Paul
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375028/
https://www.ncbi.nlm.nih.gov/pubmed/17868443
http://dx.doi.org/10.1186/gb-2007-8-9-r190
Descripción
Sumario:DNA microarrays offer the possibility of testing for the presence of thousands of micro-organisms in a single experiment. However, there is a lack of reliable bioinformatics tools for the analysis of such data. We have developed DetectiV, a package for the statistical software R. DetectiV offers powerful yet simple visualization, normalization and significance testing tools. We show that DetectiV performs better than previously published software on a large, publicly available dataset.

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