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Characterization of heterotypic interaction effects in vitro to deconvolute global gene expression profiles in cancer
BACKGROUND: Perturbations in cell-cell interactions are a key feature of cancer. However, little is known about the systematic effects of cell-cell interaction on global gene expression in cancer. RESULTS: We used an ex vivo model to simulate tumor-stroma interaction by systematically co-cultivating...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375029/ https://www.ncbi.nlm.nih.gov/pubmed/17868458 http://dx.doi.org/10.1186/gb-2007-8-9-r191 |