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Macrophage Migration Inhibitory Factor Activates Hypoxia-Inducible Factor in a p53-Dependent Manner
BACKGROUND: Macrophage migration inhibitory factor (MIF) is not only a cytokine which has a critical role in several inflammatory conditions but also has endocrine and enzymatic functions. MIF is identified as an intracellular signaling molecule and is implicated in the process of tumor progression,...
Autores principales: | Oda, Seiko, Oda, Tomoyuki, Nishi, Kenichiro, Takabuchi, Satoshi, Wakamatsu, Takuhiko, Tanaka, Tomoharu, Adachi, Takehiko, Fukuda, Kazuhiko, Semenza, Gregg L., Hirota, Kiichi |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375051/ https://www.ncbi.nlm.nih.gov/pubmed/18493321 http://dx.doi.org/10.1371/journal.pone.0002215 |
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