Detection of germline BRCA1 mutations by Multiple-Dye Cleavase Fragment Length Polymorphism (MD-CFLP) method

We describe the Multiple-Dye Cleavase Fragment Length Polymorphism (MD-CFLP) method set up for a sensitive and preliminary rapid screening of BRCA1 mutations. We analysed exons 11 and 16, which are known to cover slightly more than 70% of the whole coding region of the gene, subdivided into 4 amplic...

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Detalles Bibliográficos
Autores principales: Casadei, S, Cortesi, L, Pensotti, V, Radice, P, Pierotti, M, Amadori, D, Calistri, D
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375072/
https://www.ncbi.nlm.nih.gov/pubmed/11556835
http://dx.doi.org/10.1054/bjoc.2001.1988

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