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PDEPT: polymer-directed enzyme prodrug therapy

Polymer-directed enzyme prodrug therapy (PDEPT) is a novel two-step antitumour approach using a combination of a polymeric prodrug and polymer-enzyme conjugate to generate cytotoxic drug selectively at the tumour site. In this study the polymeric prodrug N-(2-hydroxypropyl) methacrylamide (HPMA) cop...

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Detalles Bibliográficos
Autores principales:	Satchi, R, Connors, T A, Duncan, R
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2001
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375098/ https://www.ncbi.nlm.nih.gov/pubmed/11592781 http://dx.doi.org/10.1054/bjoc.2001.2026

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