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Altered Patterns of Gene Expression Underlying the Enhanced Immunogenicity of Radiation-Attenuated Schistosomes
BACKGROUND: Schistosome cercariae only elicit high levels of protective immunity against a challenge infection if they are optimally attenuated by exposure to ionising radiation that truncates their migration in the lungs. However, the underlying molecular mechanisms responsible for the altered phen...
Autores principales: | Dillon, Gary P., Feltwell, Theresa, Skelton, Jason, Coulson, Patricia S., Wilson, R. Alan, Ivens, Alasdair C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375114/ https://www.ncbi.nlm.nih.gov/pubmed/18493602 http://dx.doi.org/10.1371/journal.pntd.0000240 |
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