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Dose and schedule-finding study of oral topotecan and weekly cisplatin in patients with recurrent ovarian cancer
Both weekly cisplatin chemotherapy and single agent topotecan have proven to be effective in recurrent ovarian cancer. Preclinical data show synergism between cisplatin and topotecan. Side effects for this combination are drug sequence dependent and predominantly haematologic. Since preclinical data...
Autores principales: | Gelderblom, H, Sparreboom, A, Jonge, M J A de, Loos, W J, Wilms, E, Mantel, M A, Hennis, B, Camlett, I, Verweij, J, Burg, M E L van der |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375148/ https://www.ncbi.nlm.nih.gov/pubmed/11710824 http://dx.doi.org/10.1054/bjoc.2001.2014 |
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