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Nucleolar damage correlates with neurotoxicity induced by different platinum drugs

Platinum-based drugs are very useful in cancer therapy but are associated with neurotoxicity in the clinic. To investigate the mechanism of neurotoxicity, dorsal root ganglia of rats treated with various platinum drugs were studied. Cell body, nuclear and nucleolar dimensions of dorsal root ganglia...

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Detalles Bibliográficos
Autores principales: McKeage, M J, Hsu, T, Screnci, D, Haddad, G, Baguley, B C
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375155/
https://www.ncbi.nlm.nih.gov/pubmed/11710838
http://dx.doi.org/10.1054/bjoc.2001.2024

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