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Nucleolar damage correlates with neurotoxicity induced by different platinum drugs
Platinum-based drugs are very useful in cancer therapy but are associated with neurotoxicity in the clinic. To investigate the mechanism of neurotoxicity, dorsal root ganglia of rats treated with various platinum drugs were studied. Cell body, nuclear and nucleolar dimensions of dorsal root ganglia...
Autores principales: | McKeage, M J, Hsu, T, Screnci, D, Haddad, G, Baguley, B C |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375155/ https://www.ncbi.nlm.nih.gov/pubmed/11710838 http://dx.doi.org/10.1054/bjoc.2001.2024 |
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