Loss of expression of HDAC-recruiting methyl-CpG-binding domain proteins in human cancer

Dysregulation of CpG-methylation is a common feature of many human cancers and tumour suppressor genes can be silenced by hypermethylation. Recently, 2 methyl-CpG-binding domain proteins have been linked to gene inactivation by their ability to recruit co-repressors and HDAC-activity to methylated g...

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Detalles Bibliográficos
Autores principales: Müller-Tidow, C, Kügler, K, Diederichs, S, Klümpen, S, Möller, M, Vogt, U, Metzger, R, Schneider, P M, Berdel, W E, Serve, H
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375156/
https://www.ncbi.nlm.nih.gov/pubmed/11710831
http://dx.doi.org/10.1054/bjoc.2001.2041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375156/
https://www.ncbi.nlm.nih.gov/pubmed/11710831
http://dx.doi.org/10.1054/bjoc.2001.2041

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