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ICI 182,780 (Fulvestrant™) – the first oestrogen receptor down-regulator – current clinical data
ICI 182,780 (Fulvestrant™) is the first in a new class of novel, steroidal, ’pure‘ antioestrogens – the oestrogen receptor (ER) down-regulators. Its unique mode of action and the absence of partial agonist activity make it a candidate for the treatment of advanced breast cancer in both pre- and post...
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Formato: | Texto |
Lenguaje: | English |
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Nature Publishing Group
2001
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375169/ https://www.ncbi.nlm.nih.gov/pubmed/11900210 http://dx.doi.org/10.1054/bjoc.2001.1982 |