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AT1 receptor is present in glioma cells; its blockage reduces the growth of rat glioma

Malignancy of neoplasms is partly dependent on angiogenesis. Angiotensin II mediates angiogenesis and transcription of growth-related factors through stimulation of the AT1 receptor (AT1R). Losartan, a drug used mostly for treatment of hypertension, binds strongly to this receptor. We found the pres...

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Detalles Bibliográficos
Autores principales: Rivera, E, Arrieta, O, Guevara, P, Duarte-Rojo, A, Sotelo, J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375243/
https://www.ncbi.nlm.nih.gov/pubmed/11720480
http://dx.doi.org/10.1054/bjoc.2001.2102