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AT1 receptor is present in glioma cells; its blockage reduces the growth of rat glioma
Malignancy of neoplasms is partly dependent on angiogenesis. Angiotensin II mediates angiogenesis and transcription of growth-related factors through stimulation of the AT1 receptor (AT1R). Losartan, a drug used mostly for treatment of hypertension, binds strongly to this receptor. We found the pres...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2001
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375243/ https://www.ncbi.nlm.nih.gov/pubmed/11720480 http://dx.doi.org/10.1054/bjoc.2001.2102 |