Cargando…

Extracellular nucleotides inhibit growth of human oesophageal cancer cells via P2Y(2)-receptors

Extracellular ATP is known to inhibit growth of various tumours by activating specific purinergic receptors (P2-receptors). Since the therapy of advanced oesophageal cancer is unsatisfying, new therapeutic approaches are mandatory. Here, we investigated the functional expression and potential antipr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Maaser, K, Höpfner, M, Kap, H, Sutter, A P, Barthel, B, von Lampe, B, Zeitz, M, Scherübl, H
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2002
Materias:	Experimental Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375265/ https://www.ncbi.nlm.nih.gov/pubmed/11870549 http://dx.doi.org/10.1038/sj.bjc.6600100

Ejemplares similares

A novel approach in the treatment of neuroendocrine gastrointestinal tumours. Targeting the epidermal growth factor receptor by gefitinib (ZD1839)
por: Höpfner, M, et al.
Publicado: (2003)

Ligands of the peripheral benzodiazepine receptor induce apoptosis and cell cycle arrest in oesophageal cancer cells: involvement of the p38MAPK signalling pathway
por: Sutter, A P, et al.
Publicado: (2003)

Oesophageal squamous cell neoplasia in head and neck cancer patients: upregulation of COX-2 during carcinogenesis
por: Maaser, K, et al.
Publicado: (2003)

Screening for oesophageal neoplasia in patients with head and neck cancer
por: Scherübl, H, et al.
Publicado: (2002)

Prognostic value of nuclear survivin expression in oesophageal squamous cell carcinoma
por: Grabowski, P, et al.
Publicado: (2003)

Inhibition of the alpha-ν integrins with a cyclic RGD peptide impairs angiogenesis, growth and metastasis of solid tumours in vivo
por: Buerkle, M A, et al.
Publicado: (2002)

Specific ligands of the peripheral benzodiazepine receptor induce apoptosis and cell cycle arrest in human colorectal cancer cells
por: Maaser, K, et al.
Publicado: (2001)

Transforming Growth Factor-β2 protects the small intestine during methotrexate treatment in rats possibly by reducing stem cell cycling
por: van't Land, B, et al.
Publicado: (2002)

Targeting EGFR and HER-2 with cetuximab- and trastuzumab-mediated immunotherapy in oesophageal squamous cell carcinoma
por: Kawaguchi, Y, et al.
Publicado: (2007)

3-Bromophenyl 6-acetoxymethyl-2-oxo-2H-1-benzopyran-3-carboxylate inhibits cancer cell invasion in vitro and tumour growth in vivo
por: Kempen, I, et al.
Publicado: (2003)

Dual blockade of EGFR and ERK1/2 phosphorylation potentiates growth inhibition of breast cancer cells
por: Lev, D C, et al.
Publicado: (2004)

Gefitinib (‘Iressa’, ZD1839) inhibits the growth response of bladder tumour cell lines to epidermal growth factor and induces TIMP2
por: Nutt, J E, et al.
Publicado: (2004)

COX-2 selective inhibition reverses the trophic properties of gastrin in colorectal cancer
por: Yao, M, et al.
Publicado: (2002)

Antitumour effects of PLC-γ1-(SH2)(2)-TAT fusion proteins on EGFR/c-erbB-2-positive breast cancer cells
por: Katterle, Y, et al.
Publicado: (2004)

In vivo evaluation of [(18)F]fluoroetanidazole as a new marker for imaging tumour hypoxia with positron emission tomography
por: Barthel, H, et al.
Publicado: (2004)

Effects of overexpression of ephrin-B2 on tumour growth in human colorectal cancer
por: Liu, W, et al.
Publicado: (2004)

Arginine deiminase: a potential inhibitor of angiogenesis and tumour growth
por: Park, I-S, et al.
Publicado: (2003)

A genome-wide expression analysis identifies a network of EpCAM-induced cell cycle regulators
por: Maaser, K, et al.
Publicado: (2008)

Adenoviruses-mediated transduction of human oesophageal carcinoma cells with the interferon-λ genes produced anti-tumour effects
por: Li, Q, et al.
Publicado: (2011)

In vitro selectivity, in vivo biodistribution and tumour uptake of annexin V radiolabelled with a positron emitting radioisotope
por: Collingridge, D R, et al.
Publicado: (2003)

Mechanisms of nordihydroguaiaretic acid-induced growth inhibition and apoptosis in human cancer cells
por: Seufferlein, T, et al.
Publicado: (2002)

Simultaneous expression of COX-2 and mPGES-1 in mouse gastrointestinal hamartomas
por: Takeda, H, et al.
Publicado: (2004)

Downregulation of Bcl-2 sensitises interferon-resistant renal cancer cells to Fas
por: Kelly, J D, et al.
Publicado: (2004)

Inherent growth advantage of (pre)malignant hepatocytes associated with nuclear translocation of pro-transforming growth factor α
por: Schausberger, E, et al.
Publicado: (2004)

Pharmacokinetics and efficacy of 2-methoxyoestradiol and 2-methoxyoestradiol-bis-sulphamate in vivo in rodents
por: Ireson, C R, et al.
Publicado: (2004)

Effect of antivascular endothelial growth factor treatment on the intratumoral uptake of CPT-11
por: Wildiers, H, et al.
Publicado: (2003)

Antimetastatic activity of a cyclooxygenase-2 inhibitor
por: Roche-Nagle, G, et al.
Publicado: (2004)

Biological significance of fluorine-18-α-methyltyrosine (FAMT) uptake on PET in patients with oesophageal cancer
por: Suzuki, S, et al.
Publicado: (2014)

The RING-H2 protein RNF11 is overexpressed in breast cancer and is a target of Smurf2 E3 ligase
por: Subramaniam, V, et al.
Publicado: (2003)

Antitumour efficacy of VEGFR2 tyrosine kinase inhibitor correlates with expression of VEGF and its receptor VEGFR2 in tumour models
por: Dev, I K, et al.
Publicado: (2004)

CYP3A4, CYP2C9 and CYP2B6 expression and ifosfamide turnover in breast cancer tissue microsomes
por: Schmidt, R, et al.
Publicado: (2004)

Forced expression of heat-shock protein 70 increases the secretion of Hsp70 and provides protection against tumour growth
por: Wang, M-H, et al.
Publicado: (2004)

Periodate-treated, non-anticoagulant heparin-carrying polystyrene (NAC-HCPS) affects angiogenesis and inhibits subcutaneous induced tumour growth and metastasis to the lung
por: Ono, K, et al.
Publicado: (2002)

Role of platelet-derived endothelial cell growth factor/thymidine phosphorylase in fluoropyrimidine sensitivity
por: de Bruin, M, et al.
Publicado: (2003)

AKT inhibition is associated with chemosensitisation in the pancreatic cancer cell line MIA-PaCa-2
por: Fahy, B N, et al.
Publicado: (2003)

Arginine deprivation, growth inhibition and tumour cell death: 2. Enzymatic degradation of arginine in normal and malignant cell cultures
por: Philip, R, et al.
Publicado: (2003)

A novel hypoxia-dependent 2-nitroimidazole KIN-841 inhibits tumour-specific angiogenesis by blocking production of angiogenic factors
por: Shimamura, M, et al.
Publicado: (2003)

Mitoxantrone resistance in a small cell lung cancer cell line is associated with ABCA2 upregulation
por: Boonstra, R, et al.
Publicado: (2004)

Diffuse EGFR staining is associated with reduced overall survival in locally advanced oesophageal squamous cell cancer
por: Gibault, L, et al.
Publicado: (2005)

Increased expression of beta 2-microglobulin in multidrug-resistant tumour cells
por: Scheffer, G L, et al.
Publicado: (2002)

Cannot write session to /tmp/vufind_sessions/sess_uhpt0667g4bj862tlf1dgvtcua