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Activation of AKT/PKB in breast cancer predicts a worse outcome among endocrine treated patients

Akt/PKB is a serine/threonine protein kinase that regulates cell cycle progression, apoptosis and growth factor mediated cell survival in association with tyrosine kinase receptors. The protein is a downstream effector of erbB-2 with implications in breast cancer progression and drug resistance in v...

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Detalles Bibliográficos
Autores principales:	Pérez-Tenorio, G, Stål, O
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2002
Materias:	Molecular and Cellular Pathology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375266/ https://www.ncbi.nlm.nih.gov/pubmed/11870534 http://dx.doi.org/10.1038/sj.bjc.6600126

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