A cyclin-dependent kinase inhibitor (p21(WAF1/CIP1)) affects thymidine incorporation in human liver cancer cells

p21(WAF1/CIP1) is a universal cyclin-dependent kinase inhibitor. To investigate the role of p21(WAF1/CIP1) in proliferation of human liver cancer cells, we examined the expression of p53, p21(WAF1/CIP1), cdk2 and cdk4 expression in two human liver cancer cell lines (HepG2 and PLC/PRF/5 cells). The e...

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Detalles Bibliográficos
Autores principales: Gong, Y, Deng, S, Zhang, M, Wang, G, Minuk, G Y, Burczynski, F
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2002
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375268/
https://www.ncbi.nlm.nih.gov/pubmed/11870547
http://dx.doi.org/10.1038/sj.bjc.6600099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375268/
https://www.ncbi.nlm.nih.gov/pubmed/11870547
http://dx.doi.org/10.1038/sj.bjc.6600099

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