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Co-transduction of Apaf-1 and caspase-9 highly enhances p53-mediated apoptosis in gliomas
Mutation of the p53 gene plays a critical role in the development of cancer and response to cancer therapy. To analyze the mechanism of cancer development and to improve cancer therapy, it is important to assess which genes are downstream components of p53 in cancers, and whether the expression leve...
Autores principales: | Shinoura, N, Sakurai, S, Shibasaki, F, Asai, A, Kirino, T, Hamada, H |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375280/ https://www.ncbi.nlm.nih.gov/pubmed/11870542 http://dx.doi.org/10.1038/sj.bjc.6600061 |
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