Cargando…

A phase II trial of the vitamin D analogue Seocalcitol (EB1089) in patients with inoperable pancreatic cancer

Inoperable cancer of the exocrine pancreas responds poorly to most conventional anti-cancer agents, and new agents are required to palliate this disease. Seocalcitol (EB1089), a vitamin D analogue, can inhibit growth, induce differentiation and induce apoptosis of cancer cell lines in vitro and can...

Descripción completa

Detalles Bibliográficos
Autores principales:	Evans, T R J, Colston, K W, Lofts, F J, Cunningham, D, Anthoney, D A, Gogas, H, de Bono, J S, Hamberg, K J, Skov, T, Mansi, J L
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2002
Materias:	Clinical
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375305/ https://www.ncbi.nlm.nih.gov/pubmed/11875725 http://dx.doi.org/10.1038/sj.bjc.6600162

Ejemplares similares

A phase II study of the vitamin D analogue Seocalcitol in patients with inoperable hepatocellular carcinoma
por: Dalhoff, K, et al.
Publicado: (2003)

A phase I study of the vitamin D analogue EB 1089 in patients with advanced breast and colorectal cancer.
por: Gulliford, T., et al.
Publicado: (1998)

Are serial measurements of CA19-9 useful in predicting response to chemotherapy in patients with inoperable adenocarcinoma of the pancreas?
por: Gogas, H., et al.
Publicado: (1998)

The vitamin D receptor agonist EB1089 can exert its antiviral activity independently of the vitamin D receptor
por: Jaratsittisin, Janejira, et al.
Publicado: (2023)

Anti-oestrogen resistant human breast cancer cell lines are more sensitive towards treatment with the vitamin D analogue EB1089 than parent MCF-7 cells
por: Larsen, S S, et al.
Publicado: (2001)

A phase II study of continuous-infusion 5-fluorouracil with cisplatin and epirubicin in inoperable pancreatic cancer.
por: Evans, T. R., et al.
Publicado: (1996)

SAT-353 The Synthetic Vitamin D Analog EB1089 Restricts Adrenocortical Tumor Proliferation in NCI-H295 Xenograft Model
por: Bueno, Ana, et al.
Publicado: (2019)

EB1089 promotes the expression of vitamin D receptor in the intestinal epithelial cell line HT-29 and reduces lipopolysaccharide-induced inflammatory response
por: Lu, Dong, et al.
Publicado: (2022)

Outpatient treatment with epirubicin and oral etoposide in patients with small-cell lung cancer.
por: Gogas, H., et al.
Publicado: (1997)

Confidences galantes, MET CD 1089/

1089 and all that: a journey into mathematics
por: Acheson, David
Publicado: (2002)

Differential and antagonistic effects of 9- cis -retinoic acid and vitamin D analogues on pancreatic cancer cells in vitro
por: Pettersson, F, et al.
Publicado: (2000)

Enzyme systems involved in glucosinolate metabolism in Companilactobacillus farciminis KB1089
por: Watanabe, Hiroko, et al.
Publicado: (2021)

Novel insights into the epidemiology of epidermolysis bullosa (EB) from the Dutch EB Registry: EB more common than previously assumed?
por: Baardman, R., et al.
Publicado: (2020)

Vitamin D receptor gene polymorphisms are associated with breast cancer risk in a UK Caucasian population
por: Bretherton-Watt, D, et al.
Publicado: (2001)

The ongoing impact of the Covid-19 pandemic on endometriosis patients: A survey of 1,089 UK patients
por: Spencer, J.I., et al.
Publicado: (2022)

1089. Analytical Performance of an Ultrasensitive Immunoassay for Detection of Clostridium difficile Toxins in Stool
por: Bartolome, Amelita, et al.
Publicado: (2018)

The effect of 1,25-dihydroxyvitamin D3 on lymphoma cell lines and expression of vitamin D receptor in lymphoma.
por: Hickish, T., et al.
Publicado: (1993)

1089. Evaluation of breakthrough infections in solid organ transplant recipients: the prospective CONTRAST cohort
por: Tazza, Beatrice, et al.
Publicado: (2022)

Blood biomarkers in the application of diagnosis and prediction of overall survival for 1089 patients with nasopharyngeal carcinoma
por: Su, Hangjiu, et al.
Publicado: (2023)

Modification of tumour radiation response in vivo by the benzamide analogue pyrazinamide.
por: Chaplin, D. J., et al.
Publicado: (1990)

Continuous EB welding of the reinforcement of the CMS conductor
por: Tavares, S S, et al.
Publicado: (2002)

Mechanisims of asthma and allergic disease – 1089. The effect of the gender of the fetus on the control of asthma during pregnancy
por: Zidan, Mohamed Helmi, et al.
Publicado: (2013)

Continuous EB welding of the reinforcement of the CMS conductor
por: Folch, R, et al.
Publicado: (2002)

CA19-9 as a prognostic factor in inoperable pancreatic cancer: the implication for clinical trials
por: Maisey, N R, et al.
Publicado: (2005)

The bisphosphonate zoledronic acid impairs membrane localisation and induces cytochrome c release in breast cancer cells
por: Senaratne, S G, et al.
Publicado: (2002)

The bisphosphonate zoledronic acid impairs membrane localisation and induces cytochrome c release in breast cancer cells
por: Senaratne, S G, et al.
Publicado: (2002)

Medically inoperable peripheral lung cancer treated with stereotactic body radiation therapy
por: Kelley, K. D., et al.
Publicado: (2015)

Inoperable Cancer
Publicado: (1901)

1089. Implementation of a Febrile Neutropenia Management Algorithm on Antibiotic Use and Outcomes: An Interrupted Time Series Analysis
por: Trinh, Trang D, et al.
Publicado: (2019)

Definitive chemoradiation in patients with inoperable oesophageal carcinoma
por: Crosby, T D L, et al.
Publicado: (2004)

CMS ECAL Barrel (EB) Integration
por: Cockerill, D
Publicado: (2006)

Differential antitumor effects of vitamin D analogues on colorectal carcinoma in culture
por: WIERZBICKA, J.M., et al.
Publicado: (2015)

Commentary. EB virus, infectious mononucleosis, and cancer: the closing of the web.
por: Evans, A. S.
Publicado: (1974)

Baclofen Withdrawal Presenting as Irritability in a Developmentally Delayed Child
por: Lim, C. Anthoney, et al.
Publicado: (2012)

1089. Health Resource Utilization and Costs Associated with Multi-Virus Infection after Allogeneic Hematopoietic Cell Transplantation
por: Hill, Joshua A, et al.
Publicado: (2020)

Response to Morita et al., Re: Continuous Deep Sedation (DOI: 10.1089/pmr.2021.0058)
por: Broeckaert, Bert
Publicado: (2022)

Thyroidectomy in Inoperable Cancer
Publicado: (1909)

Treatment of Inoperable Cancer
Publicado: (1902)

The Treatment of Inoperable Cancer
Publicado: (1902)

Cannot write session to /tmp/vufind_sessions/sess_iuu1bndbf0q2ofgg1b537c3n8o