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Anti-angiogenic effects of the thienopyridine SR 25989 in vitro and in vivo in a murine pulmonary metastasis model

Neovascularisation is a key step in tumour growth and establishment of distant metastases. We have recently demonstrated that the thienopyridine SR 25989 an enantiomer of the anti-aggregant clopidogrel (Plavix®) lacking anti-aggregant activity, inhibits endothelial cell proliferation in vitro by inc...

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Detalles Bibliográficos
Autores principales:	Mah-Becherel, M C M, Céraline, J, Deplanque, G, Chenard, M-P, Bergerat, J-P, Cazenave, J-P, Klein-Soyer, C
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2002
Materias:	Experimental Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375317/ https://www.ncbi.nlm.nih.gov/pubmed/11875746 http://dx.doi.org/10.1038/sj.bjc.6600142

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