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Superantigen reactive Vβ6(+) T cells induce perforin/granzyme B mediated caspase-independent apoptosis in tumour cells

The endogenous viral superantigen 7 in DBA/2 mice serves as a target antigen on syngeneic ESb-MP lymphoma cells for allogeneic graft-vs-leukaemia reactive cells. Allogeneic viral superantigen 7 reactive Vβ6(+) T cells are able to transfer graft-vs-leukaemia reactivity and to kill specifically viral...

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Detalles Bibliográficos
Autores principales:	Müerköster, S, Weigand, M A, Choi, C, Walczak, H, Schirrmacher, V, Umansky, V
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2002
Materias:	Experimental Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375320/ https://www.ncbi.nlm.nih.gov/pubmed/11875749 http://dx.doi.org/10.1038/sj.bjc.6600104

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