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DNA methylation and histone deacetylation associated with silencing DAP kinase gene expression in colorectal and gastric cancers
Death-associated protein kinase is a positive regulator of programmed cell death induced by interferon γ. To investigate the role of epigenetic inactivation of death-associated protein kinase in gastrointestinal cancer, we examined the methylation status of the 5′ CpG island of the death-associated...
Autores principales: | Satoh, A, Toyota, M, Itoh, F, Kikuchi, T, Obata, T, Sasaki, Y, Suzuki, H, Yawata, A, Kusano, M, Fujita, M, Hosokawa, M, Yanagihara, K, Tokino, T, Imai, K |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375414/ https://www.ncbi.nlm.nih.gov/pubmed/12087472 http://dx.doi.org/10.1038/sj.bjc.6600319 |
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