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Implication of mitochondria-derived ROS and cardiolipin peroxidation in N-(4-hydroxyphenyl)retinamide-induced apoptosis

We have studied the effect of N-(4-hydroxyphenyl)retinamide on either malignant human leukaemia cells or normal cells and investigated its mechanism of action. We demonstrate that 4HPR induces reactive oxygen species increase on mitochondria at a target between mitochondrial respiratory chain comple...

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Detalles Bibliográficos
Autores principales:	Asumendi, A, Morales, M C, Alvarez, A, Aréchaga, J, Pérez-Yarza, G
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2002
Materias:	Experimental Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375439/ https://www.ncbi.nlm.nih.gov/pubmed/12085192 http://dx.doi.org/10.1038/sj.bjc.6600356

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