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GABA transient sets the susceptibility of mIPSCs to modulation by benzodiazepine receptor agonists in rat hippocampal neurons

Benzodiazepines (BDZs) are known to increase the amplitude and duration of IPSCs. Moreover, at low [GABA], BDZs strongly enhance GABAergic currents suggesting the up-regulation of agonist binding while their action on gating remains a matter of debate. In the present study we have examined the impac...

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Detalles Bibliográficos
Autores principales: Mozrzymas, Jerzy W, Wójtowicz, Tomasz, Piast, Michał, Lebida, Katarzyna, Wyrembek, Paulina, Mercik, Katarzyna
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375456/
https://www.ncbi.nlm.nih.gov/pubmed/17855751
http://dx.doi.org/10.1113/jphysiol.2007.143602