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Detailed characterization of the mouse embryonic stem cell transcriptome reveals novel genes and intergenic splicing associated with pluripotency

BACKGROUND: Transcriptional control of embryonic stem (ES) cell pluripotency has been a subject of intense study. Transcriptional regulators including Oct4 (Oct3/4 index), Sox2 and Nanog are fundamental for maintaining the undifferentiated state. However, the ES cell transcriptome is not limited to...

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Detalles Bibliográficos
Autores principales:	Kunarso, Galih, Wong, Kee-Yew, Stanton, Lawrence W, Lipovich, Leonard
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375908/ https://www.ncbi.nlm.nih.gov/pubmed/18400104 http://dx.doi.org/10.1186/1471-2164-9-155

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