Biomarkers and Mechanisms of FANCD2 Function

Genetic or epigenetic inactivation of the pathway formed by the Fanconi anemia (FA) and BRCA1 proteins occurs in several cancer types, making the affected tumors potentially hypersensitive to DNA cross-linkers and other chemotherapeutic agents. It has been proposed that the inability of FA/BRCA-defe...

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Detalles Bibliográficos
Autores principales: Willers, Henning, Kachnic, Lisa A., Luo, Chen-Mei, Li, Li, Purschke, Martin, Borgmann, Kerstin, Held, Kathryn D., Powell, Simon N.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375970/
https://www.ncbi.nlm.nih.gov/pubmed/18483568
http://dx.doi.org/10.1155/2008/821529

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