Phosphatidylinositol 3-Kinase Mediates Bronchioalveolar Stem Cell Expansion in Mouse Models of Oncogenic K-ras-Induced Lung Cancer

BACKGROUND: Non-small cell lung cancer (NSCLC) is the most common cause of cancer-related death in Western countries. Developing more effective NSCLC therapeutics will require the elucidation of the genetic and biochemical bases for this disease. Bronchioalveolar stem cells (BASCs) are a putative ca...

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Detalles Bibliográficos
Autores principales: Yang, Yanan, Iwanaga, Kentaro, Raso, Maria Gabriela, Wislez, Marie, Hanna, Amy E., Wieder, Eric D., Molldrem, Jeffrey J., Wistuba, Ignacio I., Powis, Garth, Demayo, Francesco J., Kim, Carla F., Kurie, Jonathan M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2376060/
https://www.ncbi.nlm.nih.gov/pubmed/18493606
http://dx.doi.org/10.1371/journal.pone.0002220

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