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Longitudinal variation in O(6)-alkylguanine DNA-alkyltransferase activity in the human colon and rectum

In a systematic study of O(6)-alkylguanine DNA-alkyltransferase activity in the human colon and rectum, tumours were found to occur in regions of low activity. These results are consistent with the hypothesis that O(6)-alkylguanine DNA-alkyltransferase levels and alkylating agent exposure may be imp...

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Detalles Bibliográficos
Autores principales:	Lees, N P, Harrison, K L, Hill, E, Hall, C N, Margison, G P, Povey, A C
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2002
Materias:	Molecular and Cellular Pathology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2376118/ https://www.ncbi.nlm.nih.gov/pubmed/12107837 http://dx.doi.org/10.1038/sj.bjc.6600455

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