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Retinoids cause apoptosis in pancreatic cancer cells via activation of RAR-γ and altered expression of Bcl-2/Bax

All-trans-retinoic acid and 9-cis-retinoic acid have been reported to have inhibitory effects on pancreatic adenocarcinoma cells and we have shown that this is partly due to induction of apoptosis. In this study, the mechanisms whereby 9-cis-retinoic acid induces apoptosis in these cells were invest...

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Detalles Bibliográficos
Autores principales:	Pettersson, F, Dalgleish, A G, Bissonnette, R P, Colston, K W
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2002
Materias:	Experimental Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2376147/ https://www.ncbi.nlm.nih.gov/pubmed/12189556 http://dx.doi.org/10.1038/sj.bjc.6600496

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