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Apoptotic mechanisms in T47D and MCF-7 human breast cancer cells

To investigate the mechanisms underlying apoptosis in breast cancer cells, staurosporine was used as an apoptotic stimulus in the human breast cancer cell lines MCF-7 and T47D. Staurosporine induced dose and time dependent increases in DNA fragmentation which was abrogated by z-VAD-fmk. MCF-7 cells...

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Detalles Bibliográficos
Autores principales:	Mooney, L M, Al-Sakkaf, K A, Brown, B L, Dobson, P R M
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2002
Materias:	Experimental Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2376174/ https://www.ncbi.nlm.nih.gov/pubmed/12373608 http://dx.doi.org/10.1038/sj.bjc.6600541

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