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Endothelin-receptor antagonists are proapoptotic and antiproliferative in human colon cancer cells

Endothelin (ET)-1 can act as an autocrine/paracrine growth factor or an antiapoptotic factor in human cancers. To study the role of ET-1 in human colon cancer, proliferation and apoptosis of colon carcinoma cells was investigated using human HT-29 and SW480 colon carcinoma cells. ET-1 was secreted b...

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Detalles Bibliográficos
Autores principales:	Peduto Eberl, L, Bovey, R, Juillerat-Jeanneret, L
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2003
Materias:	Experimental Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2376352/ https://www.ncbi.nlm.nih.gov/pubmed/12618891 http://dx.doi.org/10.1038/sj.bjc.6600810

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