Role of hormonal risk factors in HER2-positive breast carcinomas

Examination of parity, age at menarche and at menopause by HER2 status in a large series of breast carcinomas showed a statistically significant increased-frequency of HER2-positive tumours in lower risk subgroups. The findings suggest a difference in the protective role of hormone-related risk fact...

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Detalles Bibliográficos
Autores principales: Balsari, A, Casalini, P, Bufalino, R, Berrino, F, Ménard, S
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2003
Materias:
Epidemiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2376362/
https://www.ncbi.nlm.nih.gov/pubmed/12671699
http://dx.doi.org/10.1038/sj.bjc.6600844
Descripción
Sumario:Examination of parity, age at menarche and at menopause by HER2 status in a large series of breast carcinomas showed a statistically significant increased-frequency of HER2-positive tumours in lower risk subgroups. The findings suggest a difference in the protective role of hormone-related risk factors between HER2-positive and -negative tumours.

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