Delayed infection, late tonsillectomy or adenoidectomy and adult leukaemia: a case–control study

In a population-based case–control study among adults in Italy, of 261 lymphoid and 313 myeloid leukaemias and 1718 controls, a later age at adenoidectomy and tonsillectomy (after age 10 years) increased considerably the risk of lymphocytic (but not myeloid) leukaemia (odds ratio 4.2, 95% confidence...

Descripción completa

Detalles Bibliográficos
Autores principales: Vineis, P, Miligi, L, Crosignani, P, Davico, L, Fontana, A, Masala, G, Nanni, O, Ramazzotti, V, Rodella, S, Stagnaro, E, Tumino, R, Viganò, C, Vindigni, C, Costantini, A S
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2003
Materias:
Epidemiolgy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2376795/
https://www.ncbi.nlm.nih.gov/pubmed/12556958
http://dx.doi.org/10.1038/sj.bjc.6600689
Descripción
Sumario:In a population-based case–control study among adults in Italy, of 261 lymphoid and 313 myeloid leukaemias and 1718 controls, a later age at adenoidectomy and tonsillectomy (after age 10 years) increased considerably the risk of lymphocytic (but not myeloid) leukaemia (odds ratio 4.2, 95% confidence interval 1.1–16.2). We propose that late infection is a proliferative stimulus for B-cells.

Ejemplares similares