Delayed infection, late tonsillectomy or adenoidectomy and adult leukaemia: a case–control study

In a population-based case–control study among adults in Italy, of 261 lymphoid and 313 myeloid leukaemias and 1718 controls, a later age at adenoidectomy and tonsillectomy (after age 10 years) increased considerably the risk of lymphocytic (but not myeloid) leukaemia (odds ratio 4.2, 95% confidence...

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Autores principales: Vineis, P, Miligi, L, Crosignani, P, Davico, L, Fontana, A, Masala, G, Nanni, O, Ramazzotti, V, Rodella, S, Stagnaro, E, Tumino, R, Viganò, C, Vindigni, C, Costantini, A S
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2003
Materias:
Epidemiolgy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2376795/
https://www.ncbi.nlm.nih.gov/pubmed/12556958
http://dx.doi.org/10.1038/sj.bjc.6600689
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author Vineis, P
Miligi, L
Crosignani, P
Davico, L
Fontana, A
Masala, G
Nanni, O
Ramazzotti, V
Rodella, S
Stagnaro, E
Tumino, R
Viganò, C
Vindigni, C
Costantini, A S
author_facet Vineis, P
Miligi, L
Crosignani, P
Davico, L
Fontana, A
Masala, G
Nanni, O
Ramazzotti, V
Rodella, S
Stagnaro, E
Tumino, R
Viganò, C
Vindigni, C
Costantini, A S
author_sort Vineis, P
collection PubMed
description In a population-based case–control study among adults in Italy, of 261 lymphoid and 313 myeloid leukaemias and 1718 controls, a later age at adenoidectomy and tonsillectomy (after age 10 years) increased considerably the risk of lymphocytic (but not myeloid) leukaemia (odds ratio 4.2, 95% confidence interval 1.1–16.2). We propose that late infection is a proliferative stimulus for B-cells.
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spelling pubmed-23767952009-09-10 Delayed infection, late tonsillectomy or adenoidectomy and adult leukaemia: a case–control study Vineis, P Miligi, L Crosignani, P Davico, L Fontana, A Masala, G Nanni, O Ramazzotti, V Rodella, S Stagnaro, E Tumino, R Viganò, C Vindigni, C Costantini, A S Br J Cancer Epidemiolgy In a population-based case–control study among adults in Italy, of 261 lymphoid and 313 myeloid leukaemias and 1718 controls, a later age at adenoidectomy and tonsillectomy (after age 10 years) increased considerably the risk of lymphocytic (but not myeloid) leukaemia (odds ratio 4.2, 95% confidence interval 1.1–16.2). We propose that late infection is a proliferative stimulus for B-cells. Nature Publishing Group 2003-01-13 2003-01-28 /pmc/articles/PMC2376795/ /pubmed/12556958 http://dx.doi.org/10.1038/sj.bjc.6600689 Text en Copyright © 2003 Cancer Research UK https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Epidemiolgy
Vineis, P
Miligi, L
Crosignani, P
Davico, L
Fontana, A
Masala, G
Nanni, O
Ramazzotti, V
Rodella, S
Stagnaro, E
Tumino, R
Viganò, C
Vindigni, C
Costantini, A S
Delayed infection, late tonsillectomy or adenoidectomy and adult leukaemia: a case–control study
title Delayed infection, late tonsillectomy or adenoidectomy and adult leukaemia: a case–control study
title_full Delayed infection, late tonsillectomy or adenoidectomy and adult leukaemia: a case–control study
title_fullStr Delayed infection, late tonsillectomy or adenoidectomy and adult leukaemia: a case–control study
title_full_unstemmed Delayed infection, late tonsillectomy or adenoidectomy and adult leukaemia: a case–control study
title_short Delayed infection, late tonsillectomy or adenoidectomy and adult leukaemia: a case–control study
title_sort delayed infection, late tonsillectomy or adenoidectomy and adult leukaemia: a case–control study
topic Epidemiolgy
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2376795/
https://www.ncbi.nlm.nih.gov/pubmed/12556958
http://dx.doi.org/10.1038/sj.bjc.6600689
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