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Functional evaluation of the apoptosome in renal cell carcinoma

Renal cell carcinoma (RCC) responds very poorly to chemo- or radiotherapy. Renal cell carcinoma cell lines have been described to be resistant to apoptosis-inducing stimuli and to lack caspase expression. Here, we provide a structural and functional assessment of the apoptosome, the central caspase-...

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Detalles Bibliográficos
Autores principales:	Gerhard, M C, Zantl, N, Weirich, G, Schliep, S, Seiffert, B, Häcker, G
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2003
Materias:	Experimental Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2376849/ https://www.ncbi.nlm.nih.gov/pubmed/14647151 http://dx.doi.org/10.1038/sj.bjc.6601436

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