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Incidence, mechanism and prognostic value of activated AKT in pancreas cancer

When activated, the serine/threonine kinase AKT mediates an antiapoptotic signal implicated in chemoresistance of various cancers. The mechanism(s) of AKT activation are unknown, though overexpression of HER-2/neu has been implicated in breast cancer. Therefore, we determined the incidence of activa...

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Detalles Bibliográficos
Autores principales:	Schlieman, M G, Fahy, B N, Ramsamooj, R, Beckett, L, Bold, R J
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2003
Materias:	Molecular and Cellular Pathology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2376856/ https://www.ncbi.nlm.nih.gov/pubmed/14647146 http://dx.doi.org/10.1038/sj.bjc.6601396

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