Cargando…
Micronuclei to detect in vivo chemotherapy damage in a p53 mutated solid tumour
Apoptosis induction and micronuclei formation were compared following cytotoxic treatments in two rat glioma differing in p53 integrity. In vitro, micronuclei emergence but not apoptosis was linked to the p53 mutated status. In vivo, micronuclei assays were more sensitive to evaluate DNA damage indu...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2003
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2376913/ https://www.ncbi.nlm.nih.gov/pubmed/12915886 http://dx.doi.org/10.1038/sj.bjc.6601163 |